Identification of a conserved conformational epitope in the VP2 protein of foot-and-mouth disease virus
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Virology"
DOI: 10.1007/s00705-017-3304-6
Abstract: Foot-and-mouth disease (FMD), caused by foot-and-mouth disease virus (FMDV), is a highly contagious infectious disease that affects domestic and wild cloven-hoofed animals worldwide. VP2 is a structural protein of FMDV. In this study, a potent… read more here.
Keywords: foot mouth; vp2 protein; conformational epitope; epitope ... See more keywords
Vaccines targeting the primary amino acid sequence and conformational epitope of amyloid‐β had distinct effects on neuropathology and cognitive deficits in EAE/AD mice
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15015
Abstract: Immunotherapeutic intervention is one of the most promising strategies for the prevention and treatment of Alzheimer's disease (AD). Although they showed great success in AD mouse models, the clinical trials of many immune approaches failed… read more here.
Keywords: conformational epitope; eae mice; targeting primary; vaccines targeting ... See more keywords
A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011370
Abstract: VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous spaces of the placenta, leading to placental malaria (PM). Relatively high… read more here.
Keywords: epitope; conformational epitope; var2csa; placental malaria ... See more keywords