DNA mismatches reveal conformational penalties in protein-DNA recognition
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DOI: 10.1038/s41586-020-2843-2
Abstract: Transcription factors recognize specific genomic sequences to regulate complex gene-expression programs. Although it is well-established that transcription factors bind to specific DNA sequences using a combination of base readout and shape recognition, some fundamental aspects… read more here.
Keywords: transcription; dna recognition; dna; protein dna ... See more keywords