Elucidation of interactions regulating conformational stability and dynamics of SARS-CoV-2 S-protein
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2021.01.012
Abstract: Ongoing COVID-19 pandemic caused by new coronavirus, SARS-CoV-2, calls for urgent developments of vaccines and antiviral drugs. The spike protein of SARS-CoV-2 (S-protein), which consists of trimeric polypeptide chains with glycosylated residues on the surface,… read more here.
Keywords: cov protein; sars cov; stability; conformational transitions ... See more keywords
Conformational stability of the tetrameric de novo designed hexcoil-Ala helical bundle
Sign Up to like & getrecommendations! Published in 2018 at "Chinese Journal of Physics"
DOI: 10.1016/j.cjph.2017.12.004
Abstract: Abstract We have performed molecular dynamics method to investigate the conformational stability of the homotetramer form of HexCoil-Ala (PDB Code 3S0R). The previous experiments showed that the chains tend to form tetramer structures. The system… read more here.
Keywords: stability tetrameric; ala; conformational stability; hexcoil ala ... See more keywords
Interpolyelectrolyte complexes of lysozyme with short poly[di(carboxylatophenoxy)phosphazene]. Binding energetics and protein conformational stability
Sign Up to like & getrecommendations! Published in 2017 at "Polymer"
DOI: 10.1016/j.polymer.2016.11.049
Abstract: Abstract Interaction of a biodegradable anionic polyphosphazene, poly[di(carboxylatophenoxy)phosphazene] (PCPP), with a model globular protein, hen egg white lysozyme, was investigated under near-physiological conditions by means of turbidimetry, high-sensitivity differential scanning and isothermal titration calorimetry (ITC).… read more here.
Keywords: poly carboxylatophenoxy; carboxylatophenoxy phosphazene; interpolyelectrolyte complexes; ligand ... See more keywords
Conformational Stability and Interplay of Helical N- and C-Terminal Domains with Implications on Major Ampullate Spidroin Assembly.
Sign Up to like & getrecommendations! Published in 2017 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.6b01713
Abstract: Major ampullate spidroin (MaSp) assembly starts in the abdomen of the spider, where spidroins are stored as a liquid dope at a high concentration. The dope is squeezed into the spinning duct, and assembly is… read more here.
Keywords: terminal domains; major ampullate; spidroin; spidroin assembly ... See more keywords
Conformational stability and structural analysis of methanethiol clusters: a revisit
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d1ra04900c
Abstract: B3LYP/cc-pV(D/T/Q)Z and CCSD/cc-pVDZ levels of theory predict three minima for both dimers and trimers of methanethiol. read more here.
Keywords: stability structural; analysis methanethiol; clusters revisit; methanethiol clusters ... See more keywords
Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 1
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aax1595
Abstract: We demonstrate that the decrease in conformational stability underlies the oncogenic activity of the N92I mutant of Rac1. Ras-related C3 botulinum toxin substrate 1 (Rac1) functions as a molecular switch by cycling between an inactive… read more here.
Keywords: ras related; n92i mutant; mutant; conformational stability ... See more keywords
Conformational Stability, TGA, and Molecular Docking Investigations of p-Coumaric Acid with Special Relevance to Anti-Cancer and Antibacterial Activity
Sign Up to like & getrecommendations! Published in 2017 at "Acta Physica Polonica A"
DOI: 10.12693/aphyspola.131.1512
Abstract: Conformational Stability, TGA, and Molecular Docking Investigations of p-Coumaric Acid with Special Relevance to Anti-Cancer and Antibacterial Activity M. Sathisha,b,∗, G. Meenakshi, S. Xavier and S. Sebastian Research Scholar, Manonmaniam Sundaranar University, Thirunelveli 627012, India… read more here.
Keywords: tga molecular; stability tga; investigations coumaric; docking investigations ... See more keywords
Effects of Receptor Specificity and Conformational Stability of Influenza A Virus Hemagglutinin on Infection and Activation of Different Cell Types in Human PBMCs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.827760
Abstract: Humans can be infected by zoonotic avian, pandemic and seasonal influenza A viruses (IAVs), which differ by receptor specificity and conformational stability of their envelope glycoprotein hemagglutinin (HA). It was shown that receptor specificity of… read more here.
Keywords: receptor specificity; infection; iavs; conformational stability ... See more keywords