Solution-Controlled Conformational Switching of an Anchored Wireframe DNA Nanostructure.
Sign Up to like & getrecommendations! Published in 2019 at "Small"
DOI: 10.1002/smll.201803628
Abstract: Self-assembled DNA origami nanostructures have a high degree of programmable spatial control that enables nanoscale molecular manipulations. A surface-tethered, flexible DNA nanomesh is reported herein which spontaneously undergoes sharp, dynamic conformational transitions under physiological conditions.… read more here.
Keywords: state; dna; controlled conformational; solution controlled ... See more keywords
Nucleotide-Dependent Dimerization and Conformational Switching of Atlastin.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0676-6_8
Abstract: A common feature of dynamin-related proteins (DRPs) is their use of guanosine triphosphate (GTP) to control protein dynamics. In the case of the endoplasmic- reticulum- (ER)-resident membrane protein atlastin (ATL), GTP binding and hydrolysis result… read more here.
Keywords: dependent dimerization; switching atlastin; nucleotide dependent; conformational switching ... See more keywords
PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2018.05.011
Abstract: Prostate-associated gene 4 (PAGE4) is an intrinsically disordered protein implicated in prostate cancer. Thestress-response kinase homeodomain-interacting protein kinase 1 (HIPK1) phosphorylates two residues in PAGE4, serine 9 and threonine 51. Phosphorylation of these two residues… read more here.
Keywords: page4; molecular dynamics; prostate cancer; dynamics simulations ... See more keywords
pH-Dependent Conformational Switching of Amide Bonds─from Full trans to Full cis and Vice Versa.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00938
Abstract: Strategies enabling the pH-dependent conformational switching of amide bonds from trans to cis, and vice versa, are yet limited in the sense that, in a suitable pH range, one rotamer may be stabilized to a… read more here.
Keywords: switching amide; cis vice; amide bonds; dependent conformational ... See more keywords
Screw sense and screw sensibility: communicating information by conformational switching in helical oligomers
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Society Reviews"
DOI: 10.1039/d2cs00982j
Abstract: Biological systems have evolved a number of different strategies to communicate information on the molecular scale. Among these, the propagation of conformational change is among the most important, being the means by which G-protein coupled… read more here.
Keywords: information; screw sense; conformational switching; communicating information ... See more keywords
MinE conformational switching confers robustness on self-organized Min protein patterns
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1719801115
Abstract: Significance Many fundamental cellular processes are spatially regulated by self-organized protein patterns, which are often based on nucleotide-binding proteins that switch their nucleotide state upon interaction with a second, activating protein. For reliable function, these… read more here.
Keywords: protein; self organized; mind; protein patterns ... See more keywords