C(sp3)-Arylation by Conformationally Accelerated Intramolecular Nucleophilic Aromatic Substitution (SNAr)
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DOI: 10.1021/acs.accounts.2c00184
Abstract: Conspectus The asymmetric synthesis of heavily substituted benzylic stereogenic centers, prevalent in natural products, therapeutics, agrochemicals, and catalysts, is an ongoing challenge. In this Account, we outline our contribution to this endeavor, describing our discovery… read more here.
Keywords: substitution; aryl; conformationally accelerated; accelerated intramolecular ... See more keywords