Summary statistic analyses can mistake confounding bias for heritability
Sign Up to like & getrecommendations! Published in 2019 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22259
Abstract: Linkage disequilibrium SCore regression (LDSC) has become a popular approach to estimate confounding bias, heritability, and genetic correlation using only genome‐wide association study (GWAS) test statistics. SumHer is a newly introduced alternative with similar aims.… read more here.
Keywords: summary statistic; confounding bias; bias heritability; statistic analyses ... See more keywords
Attention-deficit hyperactivity disorder symptoms and brain morphology: Examining confounding bias
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.78002
Abstract: Background: Associations between attention-deficit/hyperactivity disorder (ADHD) and brain morphology have been reported, although with several inconsistencies. These may partly stem from confounding bias, which could distort associations and limit generalizability. We examined how associations between… read more here.
Keywords: brain morphology; attention deficit; confounding bias; brain ... See more keywords