Calmodulin variants associated with congenital arrhythmia impair selectivity for ryanodine receptors
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DOI: 10.3389/fmolb.2022.1100992
Abstract: Among its many molecular targets, the ubiquitous calcium sensor protein calmodulin (CaM) recognizes and regulates the activity of ryanodine receptors type 1 (RyR1) and 2 (RyR2), mainly expressed in skeletal and cardiac muscle, respectively. Such… read more here.
Keywords: congenital arrhythmia; arrhythmia; variants associated; ryanodine receptors ... See more keywords