Association of Chemotherapy Timing in Pregnancy With Congenital Malformation
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DOI: 10.1001/jamanetworkopen.2021.13180
Abstract: Key Points Question Is gestational age at initiation of chemotherapy during pregnancy associated with risk of congenital malformations? Findings In this cohort study including 755 pregnant women with cancer, the risk of major congenital malformations… read more here.
Keywords: chemotherapy; pregnancy; association chemotherapy; timing pregnancy ... See more keywords
Neonatal outcomes and congenital malformations in children born after human menopausal gonadotropin and medroxyprogesterone acetate treatment cycles
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-017-4537-z
Abstract: PurposeTo investigate neonatal outcomes and congenital malformations in children born after in vitro fertilization (IVF) and vitrified embryo transfer cycles using human menopausal gonadotrophin and medroxyprogesterone acetate (hMG + MPA) treatment.MethodsWe performed a retrospective cohort study including… read more here.
Keywords: outcomes congenital; treatment; children born; malformations children ... See more keywords
Use of Nimesulide During Early Pregnancy and the Risk of Congenital Malformations: A Population-Based Study from Italy
Sign Up to like & getrecommendations! Published in 2018 at "Advances in Therapy"
DOI: 10.1007/s12325-018-0735-8
Abstract: IntroductionNimesulide is the most prescribed non-steroidal anti-inflammatory drug in Italy, and it is currently marketed in about 50 countries worldwide. The association between the use of nimesulide in early pregnancy and the risk of birth… read more here.
Keywords: risk; pregnancy; nimesulide early; use nimesulide ... See more keywords
Incidence of biliary atresia associated congenital malformations: A retrospective multicenter study in China.
Sign Up to like & getrecommendations! Published in 2017 at "Asian journal of surgery"
DOI: 10.1016/j.asjsur.2016.04.003
Abstract: BACKGROUND Some patients with biliary atresia (BA) have associated anomalies. Our study aimed to investigate the incidence of BA-associated malformations in mainland China, and compare the results with those reported in the Western literature. METHODS… read more here.
Keywords: biliary atresia; associated congenital; atresia associated; congenital malformations ... See more keywords
De novo congenital malformation frequencies in children from the Bryansk region following the Chernobyl disaster (2000–2017)
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DOI: 10.1016/j.heliyon.2020.e04616
Abstract: Background Ionizing radiation and chemical pollution can disrupt normal embryonic development and lead to congenital malformations and fetal death. We used official government statistical data for 2000–2017 to test the hypothesis that radioactive and chemical… read more here.
Keywords: multiple congenital; 2000 2017; radioactive chemical; chemical pollutants ... See more keywords
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry
Sign Up to like & getrecommendations! Published in 2018 at "The Lancet Neurology"
DOI: 10.1016/s1474-4422(18)30107-8
Abstract: BACKGROUND Evidence for the comparative teratogenic risk of antiepileptic drugs is insufficient, particularly in relation to the dosage used. Therefore, we aimed to compare the occurrence of major congenital malformations following prenatal exposure to the… read more here.
Keywords: major congenital; antiepileptic drugs; day; risk major ... See more keywords
Pathogenesis of Congenital Malformations: Possible Role of Oxidative Stress.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of perinatology"
DOI: 10.1055/s-0040-1721081
Abstract: OBJECTIVE Congenital anomalies are important causes of morbidity and mortality in children. Oxidative stress (OS) is involved in the physiopathology of pregnancy-related congenital malformations. This review summarizes the role of OS in the pathogenesis of… read more here.
Keywords: pathogenesis congenital; congenital malformations; role; oxidative stress ... See more keywords
Reported congenital malformations after exposure to non‐tumour necrosis factor inhibitor biologics: A retrospective comparative study in EudraVigilance
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15471
Abstract: To evaluate the number and nature of reported congenital malformations (CMs) after intrauterine exposure to non‐tumour necrosis factor inhibitor biologics (non‐TNFi biologics) compared to certolizumab pegol (CZP). read more here.
Keywords: necrosis factor; reported congenital; exposure non; congenital malformations ... See more keywords
Biallelic deletion in a minimal CAPN15 intron in siblings with a recognizable syndrome of congenital malformations and developmental delay
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DOI: 10.1111/cge.13920
Abstract: Calpainopathies constitute a heterogeneous group of disorders resulting from deficiencies in calpains, calcium‐specific proteases that modulate substrates by limited proteolysis. Clinical manifestations depend on tissue‐specific expression of the defective calpain and substrate specificity. CAPN15, encoding… read more here.
Keywords: developmental delay; congenital malformations; deletion minimal; capn15 ... See more keywords
The association between vascular complications during pregnancy in women with Type 1 diabetes and congenital malformations
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DOI: 10.1111/dme.13872
Abstract: To assess the association between vascular complications of diabetes and the risk of congenital malformations in pregnant women with Type 1 diabetes. read more here.
Keywords: women type; type diabetes; vascular complications; association vascular ... See more keywords
A detailed musculoskeletal study of a fetus with anencephaly and spina bifida (craniorachischisis), and comparison with other cases of human congenital malformations
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Anatomy"
DOI: 10.1111/joa.12601
Abstract: Few descriptions of the musculoskeletal system of humans with anencephaly or spina bifida exist in the literature. Even less is published about individuals in which both phenomena occur together, i.e. about craniorachischisis. Here we provide… read more here.
Keywords: human congenital; anencephaly spina; craniorachischisis; anatomy ... See more keywords