3,4-Annulated Indoles via Tandem Cyclopropane Ring-Opening/Conia-ene and Michael Addition/Conia-ene Reactions.
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DOI: 10.1021/acs.orglett.2c01810
Abstract: 4-Alkynyl indoles, when treated with a benzylidene malonate or a donor-acceptor cyclopropane in the presence of a zinc halide, furnished 3,4-hexannylated or 3,4-heptannulated products, respectively, in fair to excellent yields. The reaction proceeds via a… read more here.
Keywords: ene; via tandem; conia ene; cyclopropane ... See more keywords
Silver oxide(I) promoted Conia-ene/radical cyclization for a straightforward access to furan derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06379k
Abstract: A novel access to fused furan cores using silver oxide(I) has been developed. Mechanistic investigations indicate the involvement of a Conia-ene reaction/radical cyclization for an expedient path to complex furan derivatives. The reaction is broad… read more here.
Keywords: furan derivatives; radical cyclization; silver oxide; conia ene ... See more keywords