Gemcitabine Based Peptide Conjugate with Improved Metabolic Properties and Dual Mode of Efficacy.
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DOI: 10.1021/acs.molpharmaceut.6b00961
Abstract: Gemcitabine is a clinically established anticancer agent potent in various solid tumors but limited by its rapid metabolic inactivation and off-target toxicity. We have previously generated a metabolically superior to gemcitabine molecule (GSG) by conjugating… read more here.
Keywords: gemcitabine; gsg; gemcitabine based; peptide conjugate ... See more keywords