Long-term direct visualization of passively transferred fluorophore-conjugated antibodies.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2017.07.009
Abstract: The use of therapeutic antibodies, delivered by intravenous (IV) instillation, is a rapidly expanding area of biomedical treatment for a variety of conditions. However, little is known about how the antibodies are anatomically distributed following… read more here.
Keywords: direct visualization; antibody; fluorophore conjugated; passively transferred ... See more keywords
Controlling Conjugated Antibodies at the Molecular Level for Active Targeting Nanoparticles toward HER2-Positive Cancer Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c01090
Abstract: For active targeting nanodrug delivery systems conjugated with antibodies, both lack of control of the antibody at the molecular level and protein corona formation remarkably decreases targeting efficacy. Herein, we designed a series of silica… read more here.
Keywords: active targeting; her2 positive; molecular level; density ... See more keywords
CODEX multiplexed tissue imaging with DNA-conjugated antibodies.
Sign Up to like & getrecommendations! Published in 2021 at "Nature protocols"
DOI: 10.1038/s41596-021-00556-8
Abstract: Advances in multiplexed imaging technologies have drastically improved our ability to characterize healthy and diseased tissues at the single-cell level. Co-detection by indexing (CODEX) relies on DNA-conjugated antibodies and the cyclic addition and removal of… read more here.
Keywords: conjugated antibodies; antibodies codex; codex; dna conjugated ... See more keywords
Oligonucleotide conjugated antibodies permit highly multiplexed immunofluorescence for future use in clinical histopathology
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.25.5.056004
Abstract: Abstract. Significance: Advanced genetic characterization has informed cancer heterogeneity and the challenge it poses to effective therapy; however, current methods lack spatial context, which is vital to successful cancer therapy. Conventional immunolabeling, commonplace in the… read more here.
Keywords: future use; use clinical; highly multiplexed; conjugated antibodies ... See more keywords