Acridinium‐conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation
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DOI: 10.1002/ardp.202100400
Abstract: The epidemic of multidrug resistance (MDR) is a serious threat to public health, and new classes of antibiotics with novel mechanisms of action are in critical need. We rationally designed and efficiently synthesized three series… read more here.
Keywords: evaluation; acridinium conjugated; conjugated aromatic; heterocycles highly ... See more keywords
Synthesis of polycyano-anions conjugated with an aromatic ring
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DOI: 10.1016/j.tetlet.2017.09.012
Abstract: Abstract The synthesis of polycyano-anions, conjugated with an aryl substituent via an ethylene fragment, by the Knoevenagel condensation reaction of aromatic aldehydes with the malononitrile trimer potassium salt is described. read more here.
Keywords: polycyano anions; conjugated aromatic; aromatic ring; synthesis polycyano ... See more keywords