Acridinium‐conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation
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DOI: 10.1002/ardp.202100400
Abstract: The epidemic of multidrug resistance (MDR) is a serious threat to public health, and new classes of antibiotics with novel mechanisms of action are in critical need. We rationally designed and efficiently synthesized three series… read more here.
Keywords: evaluation; acridinium conjugated; conjugated aromatic; heterocycles highly ... See more keywords
Synthesis of polycyano-anions conjugated with an aromatic ring
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DOI: 10.1016/j.tetlet.2017.09.012
Abstract: Abstract The synthesis of polycyano-anions, conjugated with an aryl substituent via an ethylene fragment, by the Knoevenagel condensation reaction of aromatic aldehydes with the malononitrile trimer potassium salt is described. read more here.
Keywords: polycyano anions; conjugated aromatic; aromatic ring; synthesis polycyano ... See more keywords
Modular Synthesis of Conjugated Aromatic Boronate Esters by Radical Xanthate Addition
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DOI: 10.1055/a-2314-1877
Abstract: Conjugated aromatic boronate esters serve as crucial intermediates in the synthesis of pharmaceuticals and polymer materials. Traditional methods for their synthesis typically involve organoboration of aromatic ring compounds, where pre-constructions of aromatic rings were required.… read more here.
Keywords: aromatic boronate; conjugated aromatic; boronate; addition ... See more keywords