Conjugated bile acids are nutritionally re-programmable antihypertensive metabolites
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000003423
Abstract: Background: Hypertension is the largest risk factor affecting global mortality. Despite available medications, uncontrolled hypertension is on the rise, whereby there is an urgent need to develop novel and sustainable therapeutics. Because gut microbiota is… read more here.
Keywords: conjugated bile; bile acids; blood pressure; acids nutritionally ... See more keywords
Preference of Conjugated Bile Acids over Unconjugated Bile Acids as Substrates for OATP1B1 and OATP1B3
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0169719
Abstract: Bile acids, the metabolites of cholesterol, are signaling molecules that play critical role in many physiological functions. They undergo enterohepatic circulation through various transporters expressed in intestine and liver. Human organic anion-transporting polypeptides (OATP) 1B1… read more here.
Keywords: acids substrates; bile acids; unconjugated bile; conjugated bile ... See more keywords
Short communication: Chemical structure, concentration, and pH are key factors influencing antimicrobial activity of conjugated bile acids against lactobacilli.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dairy science"
DOI: 10.3168/jds.2020-19293
Abstract: Effects of chemical structure, concentration, and pH on antimicrobial activity of conjugated bile acids were investigated in 4 strains of lactobacilli. Considerable differences were observed in the antimicrobial activity between the 6 human conjugated bile… read more here.
Keywords: bile acids; antimicrobial activity; activity; chemical structure ... See more keywords