Pd(II)-catalyzed aerobic intermolecular 1,4-diamination of conjugated dienes: A regioselective [4+4] annulation for the construction of medium-ring 1,6-benzodiazocine derivatives
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.05.053
Abstract: Abstract The first metal-catalyzed oxidative intermolecular 1,4-diamination of conjugated dienes has been developed. A series of medium ring compounds were constructed via palladium-catalyzed intermolecular [4+4] annulations. Oxygen was successfully used as an oxidant instead of… read more here.
Keywords: conjugated dienes; diamination conjugated; intermolecular diamination; medium ring ... See more keywords
Cobalt-Catalyzed Divergent Cycloadditions of Alkynes with Conjugated Dienes Yielding 3-Vinylcyclobutenes, Bicyclo[3.1.0]hexenes, and Cyclohexa-1,4-dienes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03108
Abstract: A traditional cobalt catalyst system still contains undiscovered reactivity. Depending on the tertiary phosphines and substrates used, the catalytic system using CoBr2/tertiary phosphine/Zn/ZnI2 catalyzes divergent cycloadditions of internal alkynes with conjugated dienes, yielding 3-alkenylcyclobut-1-enes, bicyclo[3.1.0]hexenes,… read more here.
Keywords: alkynes conjugated; divergent cycloadditions; bicyclo hexenes; hexenes cyclohexa ... See more keywords
One-Pot and Unsymmetrical Bis-Allylation of Malononitrile with Conjugated Dienes and Allylic Alcohols.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03405
Abstract: A Pd/Ca catalytic system to promote the unsymmetrical bis-allylation of malononitrile was developed by selecting conjugated dienes and allylic alcohols as allylic reagents. This catalytic system suppressed the competitive symmetrical bis-allylation process and guaranteed the… read more here.
Keywords: bis; dienes allylic; unsymmetrical bis; bis allylation ... See more keywords
Palladium-Catalyzed Regioselective Carbonylation of 2-Trifluoromethyl-1,3-enynes to Multisubstituted Conjugated Dienes.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04331
Abstract: In this communication, a palladium-catalyzed regio- and stereoselective carbonylation of 2-trifluoromethyl-1,3-enynes to afford multisubstituted conjugated dienes has been realized. This protocol features excellent regio- and exclusive (E)-stereoselectivity and a broad substrate scope with both amines… read more here.
Keywords: trifluoromethyl enynes; palladium catalyzed; multisubstituted conjugated; carbonylation trifluoromethyl ... See more keywords
Solvent-Controlled Pd(II)-Catalyzed Aerobic Chemoselective Intermolecular 1,2-Aminooxygenation and 1,2-Oxyamination of Conjugated Dienes for the Synthesis of Functionalized 1,4-Benzoxazines.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00352
Abstract: Pd(II)-catalyzed intermolecular 1,2-aminooxygenation and 1,2-oxyamination of conjugated dienes have been developed. The chemoselective preparation of a variety of 2-functionalized and 3-functionalized 1,4-benzoxazine derivatives was accomplished via the adjustment of a coordinating solvent. Oxygen was successfully… read more here.
Keywords: intermolecular aminooxygenation; aminooxygenation oxyamination; oxyamination conjugated; conjugated dienes ... See more keywords
Catalytic Asymmetric Hydroalkoxylation and Formal Hydration and Hydroaminoxylation of Conjugated Dienes.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c11843
Abstract: The straightforward construction of stereogenic centers bearing unprotected functional groups, as in nature, has been a persistent pursuit in synthetic chemistry. Abundant applications of free enantioenriched allyl alcohol and allyl hydroxylamine motifs have made the… read more here.
Keywords: hydration; formal hydration; hydroaminoxylation conjugated; hydration hydroaminoxylation ... See more keywords
Highly Regio- and Stereoselective Catalytic Synthesis of Conjugated Dienes and Polyenes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b05421
Abstract: Conjugated dienes and polyenes are typically synthesized by sequential introduction of C═C bonds. Here, we report a practical and scalable, catalytic dienylation that is highly regio- and stereoselective for both C═C bonds. The reaction is… read more here.
Keywords: conjugated dienes; dienes polyenes; stereoselective catalytic; regio stereoselective ... See more keywords
Synthesis of conjugated dienes via palladium-catalysed aerobic dehydrogenation of unsaturated acids and amides.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02896d
Abstract: A Pd(II)-catalyzed direct aerobic dehydrogenation of γ,δ-olefinic acids and amides has been demonstrated. The present protocol dehydrogenates the least acidic amides and acids, thus replacing the traditional enolate strategy for dehydrogenation. A broad spectrum of… read more here.
Keywords: acids amides; synthesis conjugated; aerobic dehydrogenation; dienes via ... See more keywords
Biobased Polymers via Radical Homopolymerization and Copolymerization of a Series of Terpenoid-Derived Conjugated Dienes with exo-Methylene and 6-Membered Ring
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25245890
Abstract: A series of exo-methylene 6-membered ring conjugated dienes, which are directly or indirectly obtained from terpenoids, such as β-phellandrene, carvone, piperitone, and verbenone, were radically polymerized. Although their radical homopolymerizations were very slow, radical copolymerizations… read more here.
Keywords: conjugated dienes; membered ring; methylene membered; series ... See more keywords