Access to Conjugated Enynes via Allenyl Silver Formation/Cyclization/Decarboxylation Reaction Catalyzed by Silver Carbonate(I).
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02142
Abstract: Herein, we develop a novel and straightforward access to cyclic conjugated enynes catalyzed by silver carbonate/DBU from readily available substrates with good yields. The reaction is easy to set up, broad in scope, and can… read more here.
Keywords: reaction; silver; conjugated enynes; silver carbonate ... See more keywords
Palladium(II)-Catalyzed Regioselective Hydroesterification of 1,3-Conjugated Enynes with Aryl Formates.
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DOI: 10.1021/acs.orglett.2c04103
Abstract: An effective Pd-catalyzed regioselective hydroesterification of 1,3-conjugated enynes with aryl formates was developed. Under the Pd-CyDPEphos catalytic system, the conjugated enynes reacted with phenyl formates and selectively provided the 2-ester-substituted 1,3-dienes in good yields with… read more here.
Keywords: aryl formates; regioselective hydroesterification; hydroesterification conjugated; conjugated enynes ... See more keywords
Palladium(0)-Lithium Iodide Cocatalyzed Asymmetric Hydroalkylation of Conjugated Enynes with Pronucleophiles Leading to 1,3-Disubstituted Allenes.
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DOI: 10.1021/acs.orglett.9b02439
Abstract: Axially chiral 1,3-disubstituted allenes were synthesized via hydroalkylation of alkyl- or aryl-substituted conjugated enynes (readily prepared via a Sonogashira reaction) with pronucleophiles such as dimethyl malonate under the cocatalysis of DTBM-SEGPHOS-ligated palladium and lithium iodide.… read more here.
Keywords: disubstituted allenes; lithium iodide; conjugated enynes; palladium lithium ... See more keywords
Ligand-controlled copper-catalyzed 1,2 or 1,4-protoborylation of 2-trifluoromethyl-1,3-conjugated enynes
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DOI: 10.1039/d0qo00445f
Abstract: A novel ligand-controlled highly regioselective synthesis of CF3-substituted homopropargylboronates and homoallenylboronates via copper-catalyzed 1,2 or 1,4-protoborylation of 2-trifluoromethyl-1,3-conjugated enynes with B2pin2 was developed. read more here.
Keywords: trifluoromethyl conjugated; conjugated enynes; catalyzed protoborylation; ligand controlled ... See more keywords
Ni-catalyzed asymmetric hydrophosphinylation of conjugated enynes and mechanistic studies
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DOI: 10.1039/d2sc00091a
Abstract: The catalytic asymmetric synthesis of P-stereogenic phosphines is an efficient strategy to access structurally diverse chiral phosphines that could serve as organocatalysts and ligands to transition metals and motifs of antiviral drugs. Herein, we describe… read more here.
Keywords: hydrophosphinylation conjugated; could serve; catalyzed asymmetric; conjugated enynes ... See more keywords