Brønsted Acid Promoted Cyclization of Cross‐Conjugated Enynones into Dihydropyran‐4‐ones
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DOI: 10.1002/ejoc.201700423
Abstract: In triflic acid or sulfuric acid, diaryl-substituted cross-conjugated enynones undergo addition of the acid to the carbon–carbon triple bond to afford the corresponding vinyl triflates or sulfates. The vinyl triflates are stable under aqueous workup,… read more here.
Keywords: cyclization; vinyl triflates; conjugated enynones; dihydropyran ones ... See more keywords
Michael Addition of 3-Oxo-3-phenylpropanenitrile to Linear Conjugated Enynones: Approach to Polyfunctional δ-Diketones as Precursors for Heterocycle Synthesis
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DOI: 10.3390/molecules27041256
Abstract: Reaction of linear conjugated enynones, 1,5-diarylpent-2-en-4-yn-1-ones [Ar1C≡CCH=CHC(=O)Ar2], with 3-oxo-3-phenylpropanenitrile (NCCH2COPh) in the presence of sodium methoxide MeONa as a base in MeOH at room temperature for 4–26 h affords polyfunctional δ-diketones as a product of… read more here.
Keywords: linear conjugated; oxo phenylpropanenitrile; michael addition; polyfunctional diketones ... See more keywords
A General Synthesis of Cross-Conjugated Enynones through Pd Catalyzed Sonogashira Coupling with Triazine Esters
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DOI: 10.3390/molecules28114364
Abstract: The palladium-catalyzed Sonogashira coupling of α, β-unsaturated acid derivatives offers a diversity-oriented synthetic strategy for cross-conjugated enynones. However, the susceptibility of the unsaturated C-C bonds adjacent to the carbonyl group toward Pd catalysts makes the… read more here.
Keywords: triazine esters; cross conjugated; cross; conjugated enynones ... See more keywords