Colon-Targeted β3-Adrenoceptor Agonist Mirabegron Enhances Anticolitic Potency of the Drug via Potentiating the Nrf2-HO-1 Pathway.
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DOI: 10.1021/acs.molpharmaceut.4c01041
Abstract: The selective agonist of β3-adrenergic receptor mirabegron (MBG), clinically used to treat overactive bladders, exerts beneficial effects in animal models of colitis. Here, we aimed to enhance the therapeutic activity and safety of MBG as… read more here.
Keywords: colon targeted; mbg; drug; conjugated mas ... See more keywords