Dendrimer-conjugated podophyllotoxin suppresses DENA-induced HCC progression by modulation of inflammatory and fibrogenic factors.
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DOI: 10.1039/c9tx00103d
Abstract: Podophyllotoxin has been explored as an anticancer, antiviral, and antibacterial agent; however, its low water solubility and toxicity limit its use. In this study, the efficacy of a more soluble and less toxic polyamidoamine (PAMAM)… read more here.
Keywords: dendrimer conjugated; fibrogenic factors; dpodo; inflammatory fibrogenic ... See more keywords