Quercetin-conjugated superparamagnetic iron oxide nanoparticles (QCSPIONs) increases Nrf2 expression via miR-27a mediation to prevent memory dysfunction in diabetic rats
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DOI: 10.1038/s41598-020-71971-2
Abstract: Oxidative stress is one of the earliest defects involved in the development of diabetes-induced cognitive impairment. Nrf2 is the master regulator of the cellular antioxidant system can be regulated by some microRNAs. The study aimed… read more here.
Keywords: mir 27a; conjugated superparamagnetic; expression; superparamagnetic iron ... See more keywords
Effect of quercetin-conjugated superparamagnetic iron oxide nanoparticles on diabetes-induced learning and memory impairment in rats
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DOI: 10.2147/ijn.s177871
Abstract: Background Diabetes mellitus plays a causative role in cognitive decline. Newly, neuroprotective effects of flavonoids have been widely investigated in neurodegenerative diseases. Quercetin (QC) is a phyto-derived bioactive flavone with numerous beneficial activities. However, its… read more here.
Keywords: iron oxide; oxide nanoparticles; memory impairment; superparamagnetic iron ... See more keywords
Aptamer-Conjugated Superparamagnetic Ferroarabinogalactan Nanoparticles for Targeted Magnetodynamic Therapy of Cancer
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DOI: 10.3390/cancers12010216
Abstract: Nanotechnologies involving physical methods of tumor destruction using functional oligonucleotides are promising for targeted cancer therapy. Our study presents magnetodynamic therapy for selective elimination of tumor cells in vivo using DNA aptamer-functionalized magnetic nanoparticles exposed… read more here.
Keywords: therapy; conjugated superparamagnetic; aptamer conjugated; magnetodynamic therapy ... See more keywords