Antibody–drug conjugates (ADCs) for cancer therapy: Strategies, challenges, and successes
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DOI: 10.1002/jcp.27419
Abstract: Targeted delivery of therapeutic molecules into cancer cells is considered as a promising strategy to tackle cancer. Antibody–drug conjugates (ADCs), in which a monoclonal antibody (mAb) is conjugated to biologically active drugs through chemical linkers,… read more here.
Keywords: drug conjugates; drug; conjugates adcs; cancer ... See more keywords
Target Antigen Attributes and Their Contributions to Clinically Approved Antibody-Drug Conjugates (ADCs) in Haematopoietic and Solid Cancers
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DOI: 10.3390/cancers15061845
Abstract: Simple Summary Antibody-Drug Conjugates (ADCs) provide effective anti-cancer treatments. ADC development requires the identification of appropriate tumour-associated antigens that can be targeted by the ADC to effectively kill cancer cells while minimising damage to healthy… read more here.
Keywords: clinically approved; drug conjugates; conjugates adcs; target antigen ... See more keywords