Polypeptides-Drug Conjugates for Anticancer Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001974
Abstract: Polypeptides are an important class of biodegradable polymers that have been widely used in drug delivery field. Owing to the controllable synthesis and robust side chain-functionalization ability, polypeptides have long been ideal candidates for conjugation… read more here.
Keywords: drug conjugates; conjugates anticancer; polypeptides drug; drug ... See more keywords
New Salicylanilide Derivatives and Their Peptide Conjugates as Anticancer Compounds: Synthesis, Characterization, and In Vitro Effect on Glioblastoma
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.3c05727
Abstract: Pharmacologically active salicylanilides (2-hydroxy-N-phenylbenzamides) have been a promising area of interest in medicinal chemistry-related research for quite some time. This group of compounds has shown a wide spectrum of biological activities, including but not limited… read more here.
Keywords: derivatives peptide; vitro; conjugates anticancer; salicylanilide derivatives ... See more keywords
Synthesis and evaluation of thiazolidinone-pyrazole conjugates as anticancer and antimicrobial agents.
Sign Up to like & getrecommendations! Published in 2018 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2017-0191
Abstract: AIM To synthesize a series of new thiazolidinone-pyrazole hybrids (5a-o) and assess their anticancer (in vitro and in vivo) and antimicrobial activities. RESULTS The compounds 5h (against Ehrlich ascites carcinoma cells), 5e and 5i (against the… read more here.
Keywords: conjugates anticancer; pyrazole; thiazolidinone pyrazole; evaluation thiazolidinone ... See more keywords