Ubiquitin conjugating enzyme E2 M promotes apoptosis in osteoarthritis chondrocytes via Wnt/β-catenin signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.095
Abstract: In this study, the role of ubiquitin conjugating enzyme E2 M (UBE2M) and molecular mechanisms associated with osteoarthritis (OA) were explored. Cartilage tissues and corresponding healthy tissues from OA patients were isolated. Our data suggested… read more here.
Keywords: conjugating enzyme; catenin signaling; catenin; ubiquitin conjugating ... See more keywords
Computational Analysis of the Mechanism of the Ubiquitin Conjugating Enzyme Ubc13
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1579
Abstract: case we examined the sodiumdependent glucose co-transporter of Vibrio parahaemolyticus (vSGLT) which mediates galactose transport into the cytoplasm of vibrio parahaemolyticus bacteria. According literature, kinetic of cotransporter has between 5 and 6 states or conformations,… read more here.
Keywords: analysis mechanism; conjugating enzyme; analysis; computational analysis ... See more keywords
Recombinant ubiquitin-conjugating enzyme of Eimeria maxima induces immunogenic maturation in chicken splenic-derived dendritic cells and drives Th1 polarization in-vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104162
Abstract: Dendritic cells (DCs) are key linkages between innate immunity and acquired immunity. The antigens that promote the functions of DCs might be the effective candidates of novel vaccine. In this research, the ability of ubiquitin-conjugating… read more here.
Keywords: chsp dcs; dcs; conjugating enzyme; remuce ... See more keywords
Site-Specific Protein Ubiquitylation Using an Engineered, Chimeric E1 Activating Enzyme and E2 SUMO Conjugating Enzyme Ubc9
Sign Up to like & getrecommendations! Published in 2022 at "ACS Central Science"
DOI: 10.1021/acscentsci.1c01490
Abstract: Ubiquitylation—the attachment of ubiquitin (Ub) to proteins in eukaryotic cells—involves a vast number of enzymes from three different classes, resulting in heterogeneous attachment sites and ubiquitin chains. Recently, we introduced lysine acylation using conjugating enzymes… read more here.
Keywords: conjugating enzyme; sumo conjugating; enzyme ubc9; site specific ... See more keywords
A predicted NEDD8 conjugating enzyme gene identified as a Capsicum candidate Rf gene using bulk segregant RNA sequencing
Sign Up to like & getrecommendations! Published in 2020 at "Horticulture Research"
DOI: 10.1038/s41438-020-00425-7
Abstract: Cytoplasmic male sterility (CMS) is an important tool for producing F 1 hybrids, which can exhibit heterosis. The companion system, restorer-of-fertility ( Rf ), is poorly understood at the molecular level and would be valuable… read more here.
Keywords: nedd8 conjugating; conjugating enzyme; rna sequencing; segregant rna ... See more keywords
African swine fever virus encodes for an E2-ubiquitin conjugating enzyme that is mono- and di-ubiquitinated and required for viral replication cycle
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21872-2
Abstract: African swine fever virus is the etiological agent of a contagious and fatal acute haemorrhagic viral disease for which there are no vaccines or therapeutic options. The ASFV encodes for a putative E2 ubiquitin conjugating… read more here.
Keywords: swine fever; mono ubiquitinated; conjugating enzyme; african swine ... See more keywords
Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5)
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2060162
Abstract: ABSTRACT Lung adenocarcinoma (LUAD) is the main histological type of lung cancer, which is the leading cause of cancer-related deaths. Accumulating evidence has displayed that UBE2T is related to tumor progression. However, its role in… read more here.
Keywords: lung adenocarcinoma; progression; conjugating enzyme; fbln5 ... See more keywords
Prevalence of antibodies targeting ubiquitin-conjugating enzyme 2L3 and eukaryote translation elongation factor 1 α1 in Chinese Han and American Caucasian populations with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine Connections"
DOI: 10.1530/ec-22-0325
Abstract: We assessed the prevalence of two novel islet autoantibodies, those targeting ubiquitin-conjugating enzyme 2L3 (UBE2L3) and eukaryote translation elongation factor 1 α1 (eEF1A1), in type 1 diabetes mellitus (T1DM) to evaluate their utility in T1DM… read more here.
Keywords: american caucasian; targeting ubiquitin; prevalence; conjugating enzyme ... See more keywords
African swine fever virus ubiquitin-conjugating enzyme pI215L inhibits IFN-I signaling pathway through STAT2 degradation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1081035
Abstract: African swine fever virus (ASFV) is the causative agent of one of the most lethal diseases affecting domestic pig and wild boar, which is endangering the swine industry due to its rapid expansion. ASFV has… read more here.
Keywords: conjugating enzyme; stat2; ifn; ubiquitin conjugating ... See more keywords
Overexpression of Ubiquitin-Conjugating Enzyme E2C Is Associated with Worsened Prognosis in Prostate Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213873
Abstract: To evaluate the role of ubiquitin-conjugating enzyme E2C (UBE2C) in prostate cancer (PCa) progression and prognosis, the TCGA and our PCa tissue microarray cohort were included in the study. Weighted gene co-expression network analysis (WGCNA)… read more here.
Keywords: prognosis; enzyme e2c; conjugating enzyme; pca ... See more keywords