Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation
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DOI: 10.3390/molecules27165252
Abstract: The effectiveness of many anticancer drugs depends on the creation of specific metabolites that may alter their therapeutic or toxic properties. One significant route of biotransformation is a conjugation of electrophilic compounds with reduced glutathione,… read more here.
Keywords: anticancer drugs; glutathione mediated; conjugation anticancer; anticancer ... See more keywords