Multiple structural rearrangements mediated by high-plasticity regions in Atg3 are key for efficient conjugation of Atg8 to PE during autophagy
Sign Up to like & getrecommendations! Published in 2021 at "Autophagy"
DOI: 10.1080/15548627.2021.1954457
Abstract: ABSTRACT The Atg3 protein is highly homologous from yeast to human. Atg3 functions as an E2-like enzyme promoting conjugation of Atg8-family proteins to phosphatidylethanolamine (PE), a lipid molecule embedded in the growing phagophore membrane during… read more here.
Keywords: autophagy multiple; structural rearrangements; conjugation atg8; autophagy ... See more keywords
An emerging role of non-canonical conjugation of ATG8 proteins in plant response to heat stress.
Sign Up to like & getrecommendations! Published in 2023 at "Autophagy"
DOI: 10.1080/15548627.2023.2219161
Abstract: Members of the ATG8 (autophagy-related protein 8) protein family can be non-canonically conjugated to single membrane-bound organelles. The exact function of ATG8 on these single membranes remains poorly understood. Recently, using Arabidopsis thaliana as a… read more here.
Keywords: heat stress; canonical conjugation; atg8 proteins; non canonical ... See more keywords