Polyethylene Glycol Based Changes to β-Sheet Protein Conformational and Proteolytic Stability Depend on Conjugation Strategy and Location.
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DOI: 10.1021/acs.bioconjchem.7b00281
Abstract: The development of chemical strategies for site-specific protein modification now enables researchers to attach polyethylene glycol (PEG) to a protein drug at one or more specific locations (i.e., protein PEGylation). However, aside from avoiding enzyme… read more here.
Keywords: proteolytic stability; polyethylene glycol; conjugation strategy; stability ... See more keywords