Phthalimide conjugations for the degradation of oncogenic PI3K.
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DOI: 10.1016/j.ejmech.2018.03.066
Abstract: PI3K/Akt/mTOR pathway is crucial for carcinogenesis and its inhibitors have made a great progress in cancer treatment. However, there is still a great developing space for PI3K inhibitors as the acquired drug resistance hindered their… read more here.
Keywords: oncogenic pi3k; degradation; pi3k; conjugations degradation ... See more keywords