Insights into photoreceptor ciliogenesis revealed by animal models
Sign Up to like & getrecommendations! Published in 2019 at "Progress in Retinal and Eye Research"
DOI: 10.1016/j.preteyeres.2018.12.004
Abstract: Photoreceptors are polarized neurons, with very specific subcellular compartmentalization and unique requirements for protein expression and trafficking. Each photoreceptor contains an outer segment, the site of photon capture that initiates vision, an inner segment that… read more here.
Keywords: ciliogenesis; connecting cilium; photoreceptor ciliogenesis; outer segment ... See more keywords
The connecting cilium inner scaffold provides a structural foundation that protects against retinal degeneration
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001649
Abstract: Inherited retinal degeneration due to loss of photoreceptor cells is a leading cause of human blindness. These cells possess a photosensitive outer segment linked to the cell body through the connecting cilium (CC). While structural… read more here.
Keywords: degeneration; retinal degeneration; cilium inner; microscopy ... See more keywords