Articles with "connectome" as a keyword



Association of Neural Connectome With Early Experiences of Abuse in Adults

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Published in 2023 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.53082

Abstract: Key Points Question Is history of abuse associated with the intrinsic functional connectome of the adult brain independent of current psychiatric illness? Findings In this cohort study of 768 participants, individuals with abuse experienced during… read more here.

Keywords: early experiences; neural connectome; connectome early; association neural ... See more keywords

Characterizing white matter connectome abnormalities in patients with temporal lobe epilepsy using threshold‐free network‐based statistics

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Published in 2024 at "Brain and Behavior"

DOI: 10.1002/brb3.3643

Abstract: Emerging evidence illustrates that temporal lobe epilepsy (TLE) involves network disruptions represented by hyperexcitability and other seizure‐related neural plasticity. However, these associations are not well‐characterized. Our study characterizes the whole brain white matter connectome abnormalities… read more here.

Keywords: white matter; connectome; lobe epilepsy; temporal lobe ... See more keywords

Classification of schizophrenia by intersubject correlation in functional connectome

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Published in 2019 at "Human Brain Mapping"

DOI: 10.1002/hbm.24527

Abstract: Functional connectomes have been suggested as fingerprinting for individual identification. Accordingly, we hypothesized that subjects in the same phenotypic group have similar functional connectome features, which could help to discriminate schizophrenia (SCH) patients from healthy… read more here.

Keywords: schizophrenia; classification; connectome; group ... See more keywords

The Functional Connectome Mediates Associations Between Fitness and Cognition Across the Adult Lifespan

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Published in 2025 at "Human Brain Mapping"

DOI: 10.1002/hbm.70404

Abstract: Cardiorespiratory fitness (CRF) is increasingly recognized as essential for improving neural and cognitive function, especially in older age. Here, we examined a cross‐sectional sample of the Human Connectome Project (HCP) Aging dataset (ages 36–100; N = 378)… read more here.

Keywords: cognition; connectome; function; crf ... See more keywords

Individual brain metabolic connectome indicator based on Kullback-Leibler Divergence Similarity Estimation predicts progression from mild cognitive impairment to Alzheimer’s dementia

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Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"

DOI: 10.1007/s00259-020-04814-x

Abstract: Purpose Positron emission tomography (PET) with 18 F-fluorodeoxyglucose (FDG) reveals altered cerebral metabolism in individuals with mild cognitive impairment (MCI) and Alzheimer’s dementia (AD). Previous metabolic connectome analyses derive from groups of patients but do… read more here.

Keywords: similarity; connectome; cognitive impairment; brain ... See more keywords

Clinical connectome fingerprints of cognitive decline

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Published in 2021 at "NeuroImage"

DOI: 10.1016/j.neuroimage.2021.118253

Abstract: Brain connectome fingerprinting is rapidly rising as a novel influential field in brain network analysis. Yet, it is still unclear whether connectivity fingerprints could be effectively used for mapping and predicting disease progression from human… read more here.

Keywords: connectome; clinical connectome; fingerprints cognitive; brain ... See more keywords

Pre-COVID brain functional connectome features prospectively predict emergence of distress symptoms after onset of the COVID-19 pandemic

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Published in 2022 at "Psychological Medicine"

DOI: 10.1017/s0033291722002173

Abstract: Background Persistent psychological distress associated with the coronavirus disease 2019 (COVID-19) pandemic has been well documented. This study aimed to identify pre-COVID brain functional connectome that predicts pandemic-related distress symptoms among young adults. Methods Baseline… read more here.

Keywords: distress; network; brain; covid ... See more keywords

Connectome-based prediction of eating disorder-associated symptomatology.

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Published in 2022 at "Psychological medicine"

DOI: 10.1017/s0033291722003026

Abstract: BACKGROUND Despite increasing knowledge on the neuroimaging patterns of eating disorder (ED) symptoms in non-clinical populations, studies using whole-brain machine learning to identify connectome-based neuromarkers of ED symptomatology are absent. This study examined the association… read more here.

Keywords: symptomatology; eating disorder; associated symptomatology; connectome based ... See more keywords

Severity of current depression and remission status are associated with structural connectome alterations in major depressive disorder

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Published in 2019 at "Molecular Psychiatry"

DOI: 10.1038/s41380-019-0603-1

Abstract: Major depressive disorder (MDD) is associated to affected brain wiring. Little is known whether these changes are stable over time and hence might represent a biological predisposition, or whether these are state markers of current… read more here.

Keywords: status; mdd; connectome; remission ... See more keywords

Reconstruction of a connectome of single neurons in mouse brains by cross-validating multi-scale multi-modality data.

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Published in 2025 at "Nature methods"

DOI: 10.1038/s41592-025-02784-2

Abstract: Brain networks, or connectomes, have inspired research at macro-, meso- and micro-scales. However, the rise of single-cell technologies necessitates inferring connectomes consisting of individual neurons projecting throughout the brain. Her, we present a scalable approach… read more here.

Keywords: connectome single; brain; connectome; neurons mouse ... See more keywords

A large normative connectome for exploring the tractographic correlates of focal brain interventions

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Published in 2024 at "Scientific Data"

DOI: 10.1038/s41597-024-03197-0

Abstract: Diffusion-weighted MRI (dMRI) is a widely used neuroimaging modality that permits the in vivo exploration of white matter connections in the human brain. Normative structural connectomics – the application of large-scale, group-derived dMRI datasets to… read more here.

Keywords: correlates focal; brain; connectome; large normative ... See more keywords