Articles with "conotoxin txid" as a keyword



Photo by rezamehrad from unsplash

Effect of Methionine Oxidation and Substitution of α-Conotoxin TxID on α3β4 Nicotinic Acetylcholine Receptor

Sign Up to like & get
recommendations!
Published in 2018 at "Marine Drugs"

DOI: 10.3390/md16060215

Abstract: α-Conotoxin TxID was discovered from Conus textile by gene cloning, which has 4/6 inter-cysteine loop spacing and selectively inhibits α3β4 nicotinic acetylcholine receptor (nAChR) subtype. However, TxID is susceptible to modification due to it containing… read more here.

Keywords: methionine; nicotinic acetylcholine; conotoxin txid; txid ... See more keywords
Photo by rhsupplies from unsplash

Loop2 Size Modification Reveals Significant Impacts on the Potency of α-Conotoxin TxID

Sign Up to like & get
recommendations!
Published in 2023 at "Marine Drugs"

DOI: 10.3390/md21050286

Abstract: α4/6-conotoxin TxID, which was identified from Conus textile, simultaneously blocks rat (r) α3β4 and rα6/α3β4 nicotinic acetylcholine receptors (nAChRs) with IC50 values of 3.6 nM and 33.9 nM, respectively. In order to identify the effects… read more here.

Keywords: potency; txid; conotoxin txid; conotoxin ... See more keywords