Can parental consanguinity be a risk factor for the occurrence of nonsyndromic oral cleft?
Sign Up to like & getrecommendations! Published in 2019 at "Early human development"
DOI: 10.1016/j.earlhumdev.2019.06.005
Abstract: BACKGROUND The cleft lip with or without palate is the most common congenital craniofacial anomaly, presenting prevalence that varies between different ethnicities. It presents a complex and multifactorial etiology which involves genetic and environmental factors.… read more here.
Keywords: consanguinity; parental consanguinity; occurrence; cleft ... See more keywords
Does consanguinity increase the risk of mental illnesses? A population based study
Sign Up to like & getrecommendations! Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2017.01.661
Abstract: The aim of this study was to assess the impact of consanguinity on risk for mental disorders especially in primary health care-PHC settings. It was decided to ascertain prevalence of common mental disorders and consanguinity.… read more here.
Keywords: consanguinity; study; anxiety disorders; risk mental ... See more keywords
The impact of consanguinity on the frequency of inborn errors of metabolism
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Genetics and Metabolism Reports"
DOI: 10.1016/j.ymgmr.2017.11.004
Abstract: Inborn errors of metabolism (IEM) are a heterogeneous group of genetic disorders present in all ethnic groups. We investigated the frequency of consanguinity among parents of newborns with IEM diagnosed by neonatal screening. Data were… read more here.
Keywords: impact consanguinity; consanguinity; frequency; errors metabolism ... See more keywords
PRACTICE OF CONSANGUINITY AND ATTITUDES TOWARDS RISK IN THE PASHTUN POPULATION OF KHYBER PAKHTUNKHWA, PAKISTAN
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biosocial Science"
DOI: 10.1017/s0021932017000189
Abstract: Summary This study aimed to investigate the frequency of consanguineous marriages and level of understanding of consanguinity-associated genetic risks in the Pashtun population, Pakistan. Information was gathered using a detailed questionnaire completed by 1500 individuals… read more here.
Keywords: pakistan; consanguinity; pashtun population; understanding consanguinity ... See more keywords
Molecular Screening of VAX1 Gene Polymorphisms Uncovered the Genetic Heterogeneity of Nonsyndromic Orofacial Cleft Among Saudi Arabian Patients.
Sign Up to like & getrecommendations! Published in 2019 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2018.0207
Abstract: OBJECTIVE Nonsyndromic orofacial cleft (NSOFC) including cleft lip with or without cleft palate (CL±P) and cleft palate (CP) are multifactorial developmental disorders with both genetic and environmental etiological factors. In this study we investigated the… read more here.
Keywords: consanguinity; vax1 gene; nonsyndromic orofacial; association ... See more keywords
When to think outside the autozygome: Best practices for exome sequencing in “consanguineous” families
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Genetics"
DOI: 10.1111/cge.13736
Abstract: Exome sequencing (ES) is an effective diagnostic tool with a high yield in consanguineous families. However, how diagnostic yield and mode of inheritance relate to family structure has not been well delineated. We reviewed ES… read more here.
Keywords: exome sequencing; consanguinity; outside autozygome; think outside ... See more keywords
Interactions of Consanguinity and Number of Siblings with Childhood Acute Lymphoblastic Leukemia
Sign Up to like & getrecommendations! Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/7919310
Abstract: Acute lymphoblastic leukemia (ALL) is a common malignancy in children. Consanguinity has a high prevalence in developing countries and increases the probability of homozygosity for many genes which may affect ALL and its prognosis. We… read more here.
Keywords: consanguinity; consanguinity number; number siblings; lymphoblastic leukemia ... See more keywords
Incidence of inherited metabolic disorders in southern Israel: a comparison between consanguinity and non-consanguinity communities
Sign Up to like & getrecommendations! Published in 2020 at "Orphanet Journal of Rare Diseases"
DOI: 10.1186/s13023-020-01578-3
Abstract: Background Inherited metabolic disorders (IMDs) are group of rare monogenic diseases, usually derived from reduced or absent activity in a single metabolic pathway. Most of the IMDs are inherited in an autosomal recessive manner. The… read more here.
Keywords: incidence; consanguinity; imds; southern israel ... See more keywords
Family History, Consanguinity and Other Risk Factors Affecting the Prevalence of Prediabetes and Undiagnosed Diabetes Mellitus in Overweight and Obese Yemeni Adults
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s344440
Abstract: Objective Overweight and obese adults are at high risk for developing prediabetes and diabetes. The aim of this study was to measure the prevalence of prediabetes (pre-DM) and diabetes (DM) among Yemeni adults who were… read more here.
Keywords: aor value; overweight obese; prevalence; risk ... See more keywords
Detection of renal anomalies using antenatal and postnatal ultrasound: The consanguinity factor
Sign Up to like & getrecommendations! Published in 2022 at "Urology Annals"
DOI: 10.4103/ua.ua_147_19
Abstract: Introduction: Antenatal ultrasound (US) is considered the gold standard tool to detect fetal anomalies during the antenatal period. However, its highly operator dependent and maybe affected with other variables. The aim of this study to… read more here.
Keywords: consanguinity; using antenatal; anomalies using; detection renal ... See more keywords