Synthesis of Pyrroles via Consecutive 6π-Electrocyclization/Ring-Contraction of Sulfilimines
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DOI: 10.1021/jacs.1c04835
Abstract: We present a modular, synthetic entry to polysubstituted pyrroles employing readily available 2,5-dihydrothiophenes. Ring-opening of the heterocycle provides access to a panel of 1,3-dienes which undergo pyrrole formation in the presence of inexpensive chloramine-T trihydrate.… read more here.
Keywords: ring contraction; synthesis pyrroles; via consecutive; contraction ... See more keywords