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   Articles with "consensus sequence" as a keyword



Therapeutic potential of synthetic microRNA mimics based on the miR-15/107 consensus sequence

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recommendations! Published in 2025 at "Cancer Gene Therapy"

DOI: 10.1038/s41417-025-00885-w

Abstract: MicroRNA expression is frequently suppressed in cancer, and previously we demonstrated coordinate downregulation of multiple related microRNAs of the miR-15/107 group in malignant pleural mesothelioma (PM). From an alignment of the miR-15 family and the… read more here.

Keywords: consensus; therapeutic potential; mimics based; mir 107 ... See more keywords

SARS2020: An integrated platform for identification of novel coronavirus by a consensus sequence-function model

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recommendations! Published in 2021 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btaa767

Abstract: Abstract Motivation The 2019 novel coronavirus outbreak has significantly affected global health and society. Thus, predicting biological function from pathogen sequence is crucial and urgently needed. However, little work has been performed to identify viruses… read more here.

Keywords: novel coronavirus; function model; sequence; consensus sequence ... See more keywords

Importance of SUMOylation Consensus Sequence of MAFK in Regulating EMT, Tumor Growth, Stemness, and Drug Resistance.

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recommendations! Published in 2025 at "Cancer science"

DOI: 10.1111/cas.70282

Abstract: Posttranslational modification is crucial for modulating protein functions. SUMOylation is a posttranslational modification where a small ubiquitin-related (like) modifier (SUMO) conjugates to a lysine residue in the substrate proteins. SUMOylation has been shown to affect… read more here.

Keywords: resistance; mafk; sumoylation; sumoylation consensus ... See more keywords

Peptide consensus sequence determination for the enhancement of the antimicrobial activity and selectivity of antimicrobial peptides

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recommendations! Published in 2017 at "Infection and Drug Resistance"

DOI: 10.2147/idr.s118877

Abstract: The rise of multidrug-resistant bacteria is causing a serious threat to the world’s human population. Recent reports have identified bacterial strains displaying pan drug resistance against antibiotics and generating fears among medical health specialists that… read more here.

Keywords: peptide; consensus; sequence determination; consensus sequence ... See more keywords

SARS-CoV-2 Consensus-Sequence and Matching Overlapping Peptides Design for COVID19 Immune Studies and Vaccine Development

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recommendations! Published in 2020 at "Vaccines"

DOI: 10.3390/vaccines8030444

Abstract: Synthetic antigens based on consensus sequences that represent circulating viral isolates are sensitive, time saving and cost-effective tools for in vitro immune monitoring and to guide immunogen design. When based on a representative sequence database,… read more here.

Keywords: immune studies; consensus sequence; sars cov; sequence ... See more keywords