Non-canonical Transcriptional Consequences of BET Inhibition in Cancer.
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DOI: 10.1016/j.phrs.2019.104508
Abstract: Inhibition of the bromo and extra-terminal domain (BET) protein family in preclinical studies has demonstrated that BET proteins are critical for cancer progression and important therapeutic targets. Downregulation of the MYC oncogene, CDK6, BCL2 and… read more here.
Keywords: inhibition; bet inhibition; non canonical; inhibition cancer ... See more keywords