Functional consequences of chromosomal rearrangements on gene expression: not so deleterious after all?
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DOI: 10.1016/j.jmb.2019.09.010
Abstract: Chromosomes are folded and organized into topologically associated domains (TADs) which provide a framework for the interaction of enhancers with the promoter of their target gene(s). Structural rearrangements observed during evolution or in disease contexts… read more here.
Keywords: functional consequences; gene expression; chromosomal rearrangements; consequences chromosomal ... See more keywords
Origin and Consequences of Chromosomal Inversions in the virilis Group of Drosophila
Sign Up to like & getrecommendations! Published in 2018 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evy239
Abstract: Abstract In Drosophila, large variations in rearrangement rate have been reported among different lineages and among Muller’s elements. Nevertheless, the mechanisms that are involved in the generation of inversions, their increase in frequency, as well… read more here.
Keywords: drosophila; virilis group; inversions virilis; origin consequences ... See more keywords