Residue conservation and solvent accessibility are (almost) all you need for predicting mutational effects in proteins
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DOI: 10.1101/2025.02.03.636212
Abstract: Motivation Predicting how mutations impact protein biophysical properties remains a significant challenge in computational biology. In recent years, numerous predictors, primarily deep learning models, have been developed to address this problem; however, issues such as… read more here.
Keywords: solvent; conservation solvent; residue conservation; solvent accessibility ... See more keywords