Conserved Conformational Hierarchy across Functionally Divergent Glycosyltransferases of the GT-B Structural Superfamily as Determined from Microsecond Molecular Dynamics
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DOI: 10.3390/ijms22094619
Abstract: It has long been understood that some proteins undergo conformational transitions en route to the Michaelis Complex to allow chemistry. Examination of crystal structures of glycosyltransferase enzymes in the GT-B structural class reveals that the… read more here.
Keywords: microsecond molecular; open closed; molecular dynamics; structural superfamily ... See more keywords