Conserved but not critical: Trafficking and function of NaV1.7 are independent of highly conserved polybasic motifs
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2023.1161028
Abstract: Non-addictive treatment of chronic pain represents a major unmet clinical need. Peripheral voltage-gated sodium (NaV) channels are an attractive target for pain therapy because they initiate and propagate action potentials in primary afferents that detect… read more here.
Keywords: rab6a; polybasic motifs; trafficking function; critical trafficking ... See more keywords