A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04704-9
Abstract: The high rate of antigenic drift in seasonal influenza viruses necessitates frequent changes in vaccine composition. Recent seasonal H3 vaccines do not protect against swine-origin H3N2 variant (H3N2v) strains that recently have caused severe human… read more here.
Keywords: multifunctional human; human monoclonal; neutralizing antibody; conserved epitope ... See more keywords
Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.83710
Abstract: To address the ongoing SARS-CoV-2 pandemic and prepare for future coronavirus outbreaks, understanding the protective potential of epitopes conserved across SARS-CoV-2 variants and coronavirus lineages is essential. We describe a highly conserved, conformational S2 domain… read more here.
Keywords: conserved epitope; identification conserved; present spike; sars cov ... See more keywords