Engineering glutathione S-transferase with a point mutation at conserved F136 residue increases the xenobiotic-metabolizing activity.
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DOI: 10.1016/j.ijbiomac.2020.07.073
Abstract: Glutathione S-transferases (GSTs) are multifunctional enzymes that play major roles in a wide range of biological processes, including cellular detoxification, biosynthesis, metabolism, and transport. The dynamic structural scaffold and diverse functional roles of GSTs make… read more here.
Keywords: conserved f136; engineering; mutation conserved; point mutation ... See more keywords