The requirement of glycoprotein C (gC) for interindividual spread is a conserved function of gC for avian herpesviruses
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DOI: 10.1038/s41598-021-87400-x
Abstract: We have formerly shown that glycoprotein C (gC) of Gallid alphaherpesvirus 2, better known as Marek’s disease (MD) alphaherpesvirus (MDV), is required for interindividual spread in chickens. Since gC is conserved within the Alphaherpesvirinae subfamily,… read more here.
Keywords: interindividual spread; requirement glycoprotein; spread; alphaherpesvirus ... See more keywords
A conserved arginine with non‐conserved function is a key determinant of agonist selectivity in α7 nicotinic ACh receptors
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DOI: 10.1111/bph.15389
Abstract: The α7 and α4β2* (“*” denotes possibly assembly with another subunit) nicotinic acetylcholine receptors (nAChRs) are the most abundant nAChRs in the mammalian brain. These receptors are the most targeted nAChRs in drug discovery programmes… read more here.
Keywords: arginine non; conserved arginine; non conserved; function key ... See more keywords
Evidence for a Conserved Function of Eukaryotic Pantothenate Kinases in the Regulation of Mitochondrial Homeostasis and Oxidative Stress
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DOI: 10.3390/ijms24010435
Abstract: Human PANK1, PANK2, and PANK3 genes encode several pantothenate kinase isoforms that catalyze the phosphorylation of vitamin B5 (pantothenic acid) to phosphopantothenate, a critical step in the biosynthesis of the major cellular cofactor, Coenzyme A… read more here.
Keywords: function; evidence conserved; pantothenate kinase; oxidative stress ... See more keywords