Articles with "conserved ligand" as a keyword



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Suramin Targets the Conserved Ligand-Binding Pocket of Human Raf1 Kinase Inhibitory Protein

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules26041151

Abstract: Suramin was initially used to treat African sleeping sickness and has been clinically tested to treat human cancers and HIV infection in the recent years. However, the therapeutic index is low with numerous clinical side-effects,… read more here.

Keywords: protein; inhibitory protein; conserved ligand; kinase inhibitory ... See more keywords