Conserved patterns of functional organization between cortex and thalamus in mice
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2201481119
Abstract: Significance Neuroanatomical tracing provides just a partial picture of information flow in the brain, because excitatory synapses are not all equal. Some strongly drive postsynaptic targets to transfer information, whereas others weakly modulate their responsiveness.… read more here.
Keywords: information; conserved patterns; organization cortex; cortex thalamus ... See more keywords
Predicting synthetic lethal interactions using conserved patterns in protein interaction networks
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1006888
Abstract: In response to a need for improved treatments, a number of promising novel targeted cancer therapies are being developed that exploit human synthetic lethal interactions. This is facilitating personalised medicine strategies in cancers where specific… read more here.
Keywords: patterns protein; lethal interactions; topology; conserved patterns ... See more keywords
Conserved Patterns in Developmental Processes and Phases, Rather than Genes, Unite the Highly Divergent Bilateria
Sign Up to like & getrecommendations! Published in 2020 at "Life"
DOI: 10.3390/life10090182
Abstract: Bilateria are the predominant clade of animals on Earth. Despite having evolved a wide variety of body plans and developmental modes, they are characterized by common morphological traits. By default, researchers have tried to link… read more here.
Keywords: patterns developmental; processes phases; bilateria; conserved patterns ... See more keywords