Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma.
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DOI: 10.1016/j.bone.2020.115716
Abstract: Osteosarcoma is an aggressive tumor of the bone that primarily affects young adults and adolescents. Osteosarcoma is characterized by genomic chaos and heterogeneity. While inactivation of tumor protein p53 (TP53) is nearly universal other high… read more here.
Keywords: methylation; transcriptional programs; human canine; conserved transcriptional ... See more keywords