Allogeneic Hematopoietic Cell Transplantation vs Standard Consolidation Chemotherapy in Patients With Intermediate-Risk Acute Myeloid Leukemia: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.7605
Abstract: Importance The ideal postremission strategy in intermediate-risk acute myeloid leukemia (AML) in first complete remission (CR) has been a matter of debate. Objective To explore the optimal therapy for patients with intermediate-risk AML after first… read more here.
Keywords: consolidation chemotherapy; intermediate risk; consolidation; hct ... See more keywords
Clinical response to chemoradiotherapy in esophageal carcinoma is associated with survival and benefit of consolidation chemotherapy
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DOI: 10.1002/cam4.3273
Abstract: Abstract Purpose Few studies have reported the impact of the clinical response of patients with Esophageal Carcinoma to chemoradiotherapy (CRT). Our study examines the association between clinical response and pretreatment variables, survival, patterns of failure,… read more here.
Keywords: response; chemoradiotherapy; consolidation chemotherapy; benefit consolidation ... See more keywords
Pharmacokinetic/Pharmacodynamic Evaluation of Ivosidenib or Enasidenib Combined With Intensive Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed IDH1/2‐Mutant Acute Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1067
Abstract: Mutant isocitrate dehydrogenase 1/2 (mIDH1/2) proteins catalyze production of the oncometabolite D‐2‐hydroxyglutarate (2‐HG). Ivosidenib and enasidenib are oral inhibitors of mIDH1 and mIDH2, respectively. An open‐label phase 1 study is evaluating the safety and efficacy… read more here.
Keywords: combined intensive; ivosidenib enasidenib; enasidenib combined; intensive induction ... See more keywords
Neoadjuvant therapy for lateral pelvic lymph nodes: choosing between long course chemoradiation or short course radiotherapy with consolidation chemotherapy
Sign Up to like & getrecommendations! Published in 2025 at "Techniques in Coloproctology"
DOI: 10.1007/s10151-025-03177-5
Abstract: The response of lateral pelvic lymph nodes (LPLNs) to various neoadjuvant treatments has not been thoroughly investigated. This study aims to compare the effects of long-course chemoradiotherapy (LCCRT) and total neoadjuvant therapy (TNT), i.e., short-course… read more here.
Keywords: course; lateral pelvic; therapy; consolidation chemotherapy ... See more keywords
The effectiveness of consolidation chemotherapy in high-risk early-stage cervical cancer patients following concurrent chemoradiation after radical surgery.
Sign Up to like & getrecommendations! Published in 2022 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyac170
Abstract: OBJECTIVE Studies determining which early-stage cervical cancer patients with high-risk factors benefit from consolidation chemotherapy after postoperative concurrent chemoradiotherapy (CCRT) are limited and inconsistent. The aim of this study was to evaluate the value of… read more here.
Keywords: cervical cancer; consolidation chemotherapy; early stage; stage cervical ... See more keywords
Consolidation Chemotherapy Provided Survival Benefit for Esophageal Squamous Cell Carcinoma Patients Who Underwent Concurrent Chemoradiotherapy Lower Than 60 Gy
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DOI: 10.1111/1759-7714.70012
Abstract: The efficacy of consolidation chemotherapy (CCT) following concurrent chemoradiotherapy (CCRT) has not been clearly defined in esophageal squamous cell carcinoma (ESCC). This study determined which patients with stage II‐IVA ESCC benefitted from CCT. read more here.
Keywords: esophageal squamous; consolidation chemotherapy; concurrent chemoradiotherapy; squamous cell ... See more keywords
Concurrent cisplatin chemotherapy with intensity‐modulated radiotherapy followed by consolidation chemotherapy in early‐stage cervical cancer patients with high‐risk factors after radical hysterectomy
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Obstetrics and Gynaecology Research"
DOI: 10.1111/jog.16346
Abstract: To evaluate the efficacy and toxicity of consolidation chemotherapy (C‐CT) following concurrent cisplatin chemotherapy combined with intensity‐modulated radiotherapy (IMRT) in patients with early‐stage cervical cancer who present high‐risk factors (HRFs). read more here.
Keywords: modulated radiotherapy; consolidation chemotherapy; chemotherapy; concurrent cisplatin ... See more keywords
Non-operative management after chemoradiotherapy plus consolidation or sandwich (induction with bevacizumab and consolidation) chemotherapy in patients with locally advanced rectal cancer: a multicentre, randomised phase II trial (NOMINATE trial)
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DOI: 10.1136/bmjopen-2021-055140
Abstract: Introduction Total mesorectal excision (TME) and postoperative adjuvant chemotherapy following neoadjuvant chemoradiotherapy (CRT) is the standard treatment for locally advanced rectal cancer (LARC). However, neoadjuvant CRT has no recognised impact on reducing distant recurrence, and… read more here.
Keywords: survival; consolidation; trial; consolidation chemotherapy ... See more keywords
Impact of consolidation chemotherapy after delayed complete surgery in advanced epithelial ovarian cancer: a propensity score analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2022-003920
Abstract: Objectives This retrospective study aimed to assess the efficiency of consolidation chemotherapy after 6 cycles of neoadjuvant chemotherapy and delayed complete surgery on overall survival and progression-free survival among patients with advanced epithelial ovarian cancer.… read more here.
Keywords: surgery; ovarian cancer; group; consolidation chemotherapy ... See more keywords
Korean Society of Coloproctology trial of consolidation chemotherapy for locally advanced mid or low rectal cancer after neoadjuvant concurrent chemoradiotherapy: KONCLUDE multicenter radomized trial.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.3605
Abstract: 3605 Background: Recently, OPRA and RAPIDO trials showed promising results regarding the increase in pCR or clinical CR(cCR) and suggested the possibilities of non-operative management(NoM) of rectal cancer. To prove the effect of consolidation chemotherapy… read more here.
Keywords: consolidation chemotherapy; trial; rectal cancer; consolidation ... See more keywords
No operation after short course radiotherapy followed by consolidation chemotherapy in locally advanced rectal cancer: The prospective, single arm NOAHS-ARC trial.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.3_suppl.tps237
Abstract: TPS237 Background: A Watch and Wait (W&W) strategy has been advocated for selected patients with a locally advanced rectal cancer (LARC) and a clinical complete response (cCR) after neoadjuvant treatment (NAT). In this context, total… read more here.
Keywords: course radiotherapy; response; consolidation chemotherapy; chemotherapy ... See more keywords