Effect of Konjac mannan oligosaccharides on diphenoxylate-induced constipation in mice
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DOI: 10.1016/j.jff.2019.04.036
Abstract: Abstract The effects of Konjac mannan oligosaccharides (KMOS) on diphenoxylate-induced constipation in mice were investigated in the present study. After administration with KMOS at 1800 mg/kg·bw, the weight and number of black feces within 24 h, and… read more here.
Keywords: constipation; induced constipation; mannan oligosaccharides; konjac mannan ... See more keywords
Comparative pharmacodynamic, pharmacokinetic and tissue distribution of Dahuang-Gancao decoction in normal and experimental constipation mice.
Sign Up to like & getrecommendations! Published in 2019 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(19)30104-9
Abstract: Dahuang-Gancao decoction (DGD) is a classical formula, which is commonly used for reliving constipation in Chinese clinic. The aim of this study was to investigate the pharmacodynamic, pharmacokinetic and tissue distribution alternations of DGD in… read more here.
Keywords: constipation mice; tissue distribution; glycyrrhizic acid; constipation ... See more keywords
Flavonoids in Amomum tsaoko Crevost et Lemarie Ameliorate Loperamide-Induced Constipation in Mice by Regulating Gut Microbiota and Related Metabolites
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DOI: 10.3390/ijms24087191
Abstract: Amomum tsaoko (AT) is a dietary botanical with laxative properties; however, the active ingredients and mechanisms are still unclear. The active fraction of AT aqueous extract (ATAE) for promoting defecation in slow transit constipation mice… read more here.
Keywords: gut microbiota; amomum tsaoko; constipation; constipation mice ... See more keywords