Prothrombin R541W Mutation Impairs Protein C Activation and Constitutes a New Genetic Risk Factor for Venous Thrombosis
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DOI: 10.1182/blood-2019-127694
Abstract: Defective protein C (PC) pathway predisposes patients to venous thromboembolism (VTE)and is mostly, but not exclusively, attributed tohereditary PC or protein S (PS) deficiencies and activated PC resistance caused by factor V Leiden mutation. In… read more here.
Keywords: medicine; venous thrombosis; constitutes new; prothrombin ... See more keywords