HP1 proteins regulate nucleolar structure and function by secluding pericentromeric constitutive heterochromatin
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1159
Abstract: Abstract Nucleoli are nuclear compartments regulating ribosome biogenesis and cell growth. In embryonic stem cells (ESCs), nucleoli containing transcriptionally active ribosomal genes are spatially separated from pericentromeric satellite repeat sequences packaged in largely repressed constitutive… read more here.
Keywords: heterochromatin; hp1; function; pch ... See more keywords
Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks
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DOI: 10.1093/nar/gky368
Abstract: Abstract The replication of the genome is a highly organized process, both spatially and temporally. Although a lot is known on the composition of the basic replication machinery, how its activity is regulated is mostly… read more here.
Keywords: replication timing; maintenance; silencing marks; constitutive heterochromatin ... See more keywords
Constitutive heterochromatin in chromosomes of duck hybrids and goose hybrids
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DOI: 10.3382/ps/pew318
Abstract: &NA; Constitutive heterochromatin is a highly condensed fraction of chromatin in chromosomes. It is characterized by a high degree of polymorphism. Heterochromatin is located in the centromeric, telomeric, and interstitial parts of chromosomes. We used… read more here.
Keywords: heterochromatin chromosomes; heterochromatin; chromosomes goose; constitutive heterochromatin ... See more keywords
Mechanisms governing the accessibility of DNA damage proteins to constitutive heterochromatin
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DOI: 10.3389/fgene.2022.876862
Abstract: Chromatin is thought to regulate the accessibility of the underlying DNA sequence to machinery that transcribes and repairs the DNA. Heterochromatin is chromatin that maintains a sufficiently high density of DNA packing to be visible… read more here.
Keywords: heterochromatin; constitutive heterochromatin; accessibility; dna damage ... See more keywords
Maps of Constitutive-Heterochromatin Distribution for Four Martes Species (Mustelidae, Carnivora, Mammalia) Show the Formative Role of Macrosatellite Repeats in Interspecific Variation of Chromosome Structure
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DOI: 10.3390/genes14020489
Abstract: Constitutive-heterochromatin placement in the genome affects chromosome structure by occupying centromeric areas and forming large blocks. To investigate the basis for heterochromatin variation in the genome, we chose a group of species with a conserved… read more here.
Keywords: chromosome structure; four martes; variation; constitutive heterochromatin ... See more keywords