Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance.
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DOI: 10.1158/2326-6066.cir-16-0400
Abstract: Tumors use various mechanisms to avoid immune destruction. Cyclooxygenase-2 (COX-2) expression may be a driver of immune suppression in melanoma, but the mechanisms involved remain elusive. Here, we show that COX-2 expression drives constitutive expression… read more here.
Keywords: expression human; ido1 expression; constitutive ido1; expression ... See more keywords