Articles with "constitutive neoantigen" as a keyword



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Abstract 5475: Improved prediction of immunotherapy responses by constitutive neoantigen load and LINE-1 methylation

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-5475

Abstract: Previous biomarkers such as PD-L1 expression, tumor mutation burden (TMB), and neoantigen load have limited accuracy in predicting responses to immune checkpoint inhibitor (ICI) therapy. In this work, we propose an improved predictor of ICI… read more here.

Keywords: neoantigen load; load; constitutive neoantigen; line methylation ... See more keywords