Articles with "construction densely" as a keyword



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Asymmetric construction of densely functionalized three-dimensional aza-tetracyclic scaffolds for drug discovery.

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Published in 2022 at "Chemical communications"

DOI: 10.1039/d2cc05700j

Abstract: Asymmetric construction of densely functionalized three-dimensional aza-tetracyclic scaffolds were achieved by intramolecular Diels-Alder reaction of bicyclic precursors derived from L-tyrosine. Three substituents were systematically introduced into the developed scaffolds in various combinations, demonstrating their high… read more here.

Keywords: construction densely; functionalized three; asymmetric construction; dimensional aza ... See more keywords